CN
Discovery Biomarker

Tissue-based Biomarker – Pathology Lab 

Partnership with world’s renowned Pathology lab

  • Access over 40 pathologists at Targos.
  • Collaboration on global trials
  • Pathologists trained by Targos

Technology platforms

  • H&E, IHC
  • FISH& DISH

Automated instruments with high throughput capability

  • Leica Microtome & Cryotome
  • Roche Ventana Benchmark Ultra
  • Zeiss multi-head microscope
  • Zeiss Axio Imager 2 Fluorescence microscope
  • Zeiss Axio Digital Scanner

GCP compliance and CAP accreditation

Establishing multiplexed tissue staining

  • Quantitative pathology to interrogate protein expression in cancer
  • Invested Vectra – multispectral imaging
  • Florescence, bright-field and multispectral
  • Tissue microarrays and whole tissue sections
  • Single or 200-slide capacity
  • inform to guide acquisition of higher power images automatically

 

Special Staining

  • Oil Red O stain
  • Sirius Red stain
  • Trichrome stain (Masson)
  • Von Kossa (Calcium Stain)
  • Periodic Acid-Schiff stain
  • Wright-Giemsa stain

 

Optimization of Human Tumor Dissociation Process to Eliminate hTIM-3 and hLAG-3 Degradations

 

Cell-based Biomarker (Flow Cytometry Lab)

Measurement of cellular biomarkers (up to 18-color)

  • Surface phenotyping
  • Intracellular markers

Aseptic 4-channel cell sorting

Signaling pathway studies

Cytokine expression/production studies

Cell cycle/apoptosis

GCP compliance and CAP accreditation